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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DDX10 All Species: 23.33
Human Site: S539 Identified Species: 39.49
UniProt: Q13206 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13206 NP_004389.2 875 100888 S539 V I E P R A P S L T N D E V E
Chimpanzee Pan troglodytes XP_001141618 875 100804 S539 V I E P R A P S L T N D E V E
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_536583 871 100167 S540 V I E P R A P S L T N D E V E
Cat Felis silvestris
Mouse Mus musculus Q80Y44 875 100720 S540 A V P P R A P S L P N D E A D
Rat Rattus norvegicus NP_001100290 874 101001 S540 A I Q P R A P S L T S D E V E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509692 859 98483 S541 Q R E S P A S S L S N D E V E
Chicken Gallus gallus Q5ZJF6 875 100138 S548 Q N K N T I S S L N K E G M E
Frog Xenopus laevis NP_001089088 663 75544 L393 F P A V S W V L Q L D C P E D
Zebra Danio Brachydanio rerio XP_001922220 864 99178 S537 S S T A G H Q S E D E L Q S F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_573230 826 92827 P532 L A V T P R V P F L E K F L W
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780056 867 98194 S533 Q R L S G T P S S S Q P I T E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FFT9 739 83563 G469 V K Y P D L Q G V A Q R A F I
Baker's Yeast Sacchar. cerevisiae P20448 770 87174 G493 A P K I K M K G M K T I E Q A
Red Bread Mold Neurospora crassa Q7RZ35 823 92654 E525 M S S G S D T E G S D G E I R
Conservation
Percent
Protein Identity: 100 99 N.A. 89 N.A. 85.1 86.2 N.A. 73.1 66.8 54.1 59.6 N.A. 42.2 N.A. N.A. 48.4
Protein Similarity: 100 99.7 N.A. 94.2 N.A. 92.4 93.1 N.A. 84 79.6 64.2 76.5 N.A. 62.2 N.A. N.A. 68.5
P-Site Identity: 100 100 N.A. 100 N.A. 60 80 N.A. 60 20 0 6.6 N.A. 0 N.A. N.A. 20
P-Site Similarity: 100 100 N.A. 100 N.A. 73.3 93.3 N.A. 66.6 40 13.3 13.3 N.A. 13.3 N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. 36.9 38.7 40.2
Protein Similarity: N.A. N.A. N.A. 57.6 56.9 57.7
P-Site Identity: N.A. N.A. N.A. 13.3 6.6 6.6
P-Site Similarity: N.A. N.A. N.A. 20 26.6 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 22 8 8 8 0 43 0 0 0 8 0 0 8 8 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % C
% Asp: 0 0 0 0 8 8 0 0 0 8 15 43 0 0 15 % D
% Glu: 0 0 29 0 0 0 0 8 8 0 15 8 58 8 50 % E
% Phe: 8 0 0 0 0 0 0 0 8 0 0 0 8 8 8 % F
% Gly: 0 0 0 8 15 0 0 15 8 0 0 8 8 0 0 % G
% His: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 29 0 8 0 8 0 0 0 0 0 8 8 8 8 % I
% Lys: 0 8 15 0 8 0 8 0 0 8 8 8 0 0 0 % K
% Leu: 8 0 8 0 0 8 0 8 50 15 0 8 0 8 0 % L
% Met: 8 0 0 0 0 8 0 0 8 0 0 0 0 8 0 % M
% Asn: 0 8 0 8 0 0 0 0 0 8 36 0 0 0 0 % N
% Pro: 0 15 8 43 15 0 43 8 0 8 0 8 8 0 0 % P
% Gln: 22 0 8 0 0 0 15 0 8 0 15 0 8 8 0 % Q
% Arg: 0 15 0 0 36 8 0 0 0 0 0 8 0 0 8 % R
% Ser: 8 15 8 15 15 0 15 65 8 22 8 0 0 8 0 % S
% Thr: 0 0 8 8 8 8 8 0 0 29 8 0 0 8 0 % T
% Val: 29 8 8 8 0 0 15 0 8 0 0 0 0 36 0 % V
% Trp: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 8 % W
% Tyr: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _